Intracameral 0.5% phenylephrine—a safe solution?

Safety of prophylactic intracameral moxifloxacin 0.5% ophthalmic solution in cataract surgery patients.

PURPOSE To determine the safety of prophylactic intracameral moxifloxacin 0.5% ophthalmic solution (Vigamox) in patients having cataract surgery. SETTING American Eye Center, Manila, Philippines. METHODS Preoperative and 1-month postoperative anterior chamber reaction, corneal endothelial cell density, and corneal thickness were assessed in 65 eyes that had cataract surgery with intracamera...

Safety of prophylactic intracameral moxifloxacin ophthalmic solution after cataract surgery in patients with penetrating keratoplasty.

AIM To determine the safety of prophylactic intracameral moxifloxacin after cataract surgery in patients with penetrating keratoplasty (PKP). METHODS In this retrospective study of consecutive patients who had phacoemulsification cataract surgery after PKP, were treated with intracameral moxifloxacin 0.5% ophthalmic solution (0.5 mg/0.1 mL). The main outcome measures were anterior chamber rea...

Intracameral antibiotic: the Vancomycin conundrum.

Delayed complications of cataract surgery are uncommon. Where previously endophthalmitis was the most feared complication now there is a new contenderHaemorrhagic Occlusive Retinal Vasculitis (HORV). These two complications can present a week after surgery and result in no perception of light. Vancomycin has been used extensively as a prophylaxis against endopthalmitis, and is now thought to be...

Intracameral Mydriatics in Cataract Surgery

Pharmacokinetics of intracameral voriconazole injection.

Elimination of voriconazole after intracameral injection exhibited an exponential decay with a half-life of 22 min. Voriconazole levels in the vitreous humor were below the detectable limit. The aqueous concentrations achieved with a 25-microg dose during the first 2 h were greater than the previously reported MICs of organisms most involved in fungal endophthalmitis. A rapid decline in intraca...